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Name: cagrilintide and semaglutide New in the August 14, 2025, issue of NEJM: Cagrilintide–Semaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) https://nej.md/444aW7f Cagrilintide–Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial) https://nej.md/4ehQwLk
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Retatrutide, Eli Lilly's triple-hormone GLP-1, produced an average weight loss of about 71 lbs in its latest Phase 3 trial. Up to 65% of participants reached a healthy BMI. Still in trials,

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